Atelectasis, Shunt, and Worsening Oxygenation Following Reduction of Respiratory Rate in Healthy Pigs Undergoing ECMO: An Experimental Lung Imaging Study

Rationale: Reducing the respiratory rate during extracorporeal membrane oxygenation (ECMO) decreases the mechanical power, but it might induce alveolar de-recruitment.Dissecting de-recruitment due to lung edema vs.the fraction due to hypoventilation may be challenging in injured lungs.Objectives: We characterized changes in lung physiology (primary

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